Defense Secretary Jim Mattis says he has directed the Pentagon’s watchdog to examine the circumstances of the Air Force’s failure to report the Texas church shooter’s domestic violence conviction to the FBI.
Mattis says we have to “find out what’s going on.”
Under Pentagon rules, convictions of military personnel in crimes like assault should be shared with the FBI for its National Criminal Information Center database. Devin Patrick Kelley, the gunman in the Nov. 5 attack, was convicted of assault against his wife and stepson in an Air Force court-martial in 2012.
Army Reserve soldiers of American Samoa will soon train at the first indoor rifle range in the Army Reserve, a Modular Small Arms Range scheduled for a grand opening the end of April 2019.
“The sons and daughters of American Samoa serving in the Armed Forces will have the single best indoor training facility in the Army,” Brigadier Gen. Douglas Anderson, 9th Mission Support Command Commanding General, said. “We are providing our soldiers in American Samoa state of the art training facilities and the ability to conduct training at home, keeping these citizen soldiers with their families and employers to the maximum extent possible.”
Prior to this construction, soldiers of the region flew to Hawaii to conduct their regular required training. Now with the training site locally based, soldiers will be able to complete their annual requirements without having to leave home to do so.
“We need to train our soldiers to be ready so that when they are called to go in harms’ way they can meet the challenge but also defeat the enemy,” Jon Lee, 9th MSC civilian executive officer, said. “They are all serving our country to protect our freedoms. So we are giving them the newest and best to train and succeed.”
(U.S. Army photo)
“We have a commitment to the community to build the soldiers’ readiness so they can be ready at their home station which lessens their time away from their families,” Lee said.
Lee, a retired general officer and former 100th Battalion, 442nd Infantry Regiment commander, his first unit was the American Samoa-based 100th Battalion, B Co., in 1984. Years later he deployed with American Samoan soldiers in 2004 to Operation Iraqi Freedom and recalled what the soldiers previously endured in order to train for said deployment.
“The first time the 100th Battalion was mobilized to go to Iraq, the soldiers of American Samoa spent almost 9 months to train and get certified,” he recalled. “So that’s almost two years they were away from home. It shouldn’t be that way.”
“The Army is committed to the training and readiness, for the people of American Samoa who have sons and daughters, brothers and sisters, wives, husbands who serve, and we are bringing in a State of the Art facility, the first of its kind for their sons and daughters,” Lee said. “We are bringing them the best of the best so that they can maximize to train in their local area.”
“We now have a greater chance to focus on the mission and training instead of spending a whole day at the shooting range,” Staff Sgt. Faiupu Tagaleo’o, unit supply sergeant for Theater Support Group- Pacific, American Samoa. “Now we don’t have to travel 5,000 miles or 10,000 miles to qualify with weapons. We can do it right here at home.”
Other Army Reserve soldiers of American Samoa expressed similar sentiments.
(U.S. Army photo)
“I support the building of MSAR because I won’t have to wait a whole year for Annual Training to shoot,” Sgt. K. Moetala, C. Co. 100th Battalion, 442nd Inf. Regt. said. “Also I get to train but I will be spending more time with my family.”
Furthermore, Lee stated, the MSAR is safe.
“It has zero escape for a round, 100 percent containment, from the ceiling to the walls to the ground,” he specified. “We issue ammo inside the building, with the doors closed and lock the building while firing. We take accountability of spent casings. We do accountability before we open the room again.”
The MSAR is also environmentally safe, with a filtration system so the fumes and gases released from the weapons are filtered. An additional benefit of the indoor facility, not only is it environmentally sound, but contains literal sound within from insulation.
“Noise abatement measures have been taken so that our community neighbors aren’t listening to the sounds of the rifle range during a training weekend,” said Anderson.
While maintaining U.S. Army Safety standards during use of the facility, the existence of the facility will also enable law enforcement and other security and protection entities such as the Department of Homeland Security and the Coast Guard, access to train.
Through the duration of construction, 9th MSC has hosted three community town halls continuing the relationship with its neighbors.
“Thanks to the community for participating in the three community engagements that we’ve held,” Anderson said. “Safety is a priority for the Army Reserve and the Modular Small Arms Range is safe and we welcome any opportunity to show this.”
Costumes, candy, Halloween parties, and trick or treating are common ways to celebrate All Hallows Eve. Another way some choose to take part in is by going to a “haunted house.”
For some, haunted houses are all too real.
Many Team Shaw members have heard rumors of some buildings on base that are supposedly haunted, but few have actually had experiences with the paranormal. The following stories have been told by Shaw housing residents who claim to have had encounters.
“The old base housing was very haunted so I’d say yes it’s possible the new ones are too,” said a Team Shaw spouse. “We had so many creepy experiences in the old housing. My oldest would scream bloody murder and just point at something in his room and refuse to go in there. At night, we’d lay in bed and could hear something downstairs slamming cabinets closed.”
Others said they have seen floating orbs of light on camera, had home devices turn on by themselves and heard doors open and close or bangs in their home.
Another member said she is “creeped out” but has come to terms with the entity in her home. Whenever she decides to turn in for the night, she now says, “Alright haunts. I’m going to bed. It’s time for you to go on home.”
In August of 2015, Heather Ingle, Team Shaw spouse, moved to Shaw Air Force Base, South Carolina, with her active duty husband and two young daughters.
“When we came here, (the girls) were refusing to sleep in their room,” Ingle said of her new home. “(My youngest daughter) was still pretty young, and she wouldn’t even go in there,”
“They just would not go in the room,” said Ingle. “(My eldest daughter) kept saying, ‘There is a scary lady in there.’ I told her, ‘There is nobody in this house. There’s nobody in here.’ We would just battle night after night after night that they wanted to sleep in bed with me, both of them.”
During this time in her life, Ingle was working in Columbia, South Carolina, and would get home late, while her daughters would stay at a friend’s home until she was able to pick them up and take them home.
Ingle stated one night she and her daughters got home around midnight after a long day of work. Her children were exhausted, but still argued to sleep with her in her bedroom.
She, then, went into their bedroom, closed the door, and screamed at whatever entity was there to go away, saying it wasn’t welcome here. Then, Ingle shouted out a blessing she was told to use by a friend.
According to Ingle, ever since that night, there have been no experiences. The girls do not see the ‘scary lady’ anymore.
So, if Team Shaw members hear someone shout “Boo!” while enjoying a “haunted house” this Halloween, look around. There may not be anyone there.
This article originally appeared on DVIDS. Follow @DVIDSHub on Twitter.
The Marine Corps presented the Air Medal to three U.S. Marines on July 24, 2018, at Marine Air Station Miramar, California, for their actions while crewing a CH-53E Super Stallion that caught fire off the coast of Okinawa, Japan, during aerial refueling operations.
Capt. Molly A. O’Malley stands during an award ceremony where she and two other Marines received the Air Medal.
(U.S. Marine Corps Sgt. Dominic Romero)
The awards were presented to Capt. Ryan J. Boyer, Capt. Molly A. O’Malley, and Sgt. Garrett D. Mills of Marine Heavy Helicopter Squadron (HMH) 462, Marine Aircraft Group (MAG) 16. The Marines were serving in Japan last year and were conducting operations near Okinawa’s Northern Training Area, an area often used for jungle training.
The helicopter itself was almost completely destroyed by the fire. The engine, most of the rotor blades, and the fuselage are visible as just a pile of slag in the Japanese field in images and video released by Japanese media after the crash.
Additional helicopters rushed to the scene to secure the crew and passengers and another CH-53 came on station with a helibucket to drop water and control the flames until Japanese firefighters and American first-responders from the nearby base could respond.
The quick actions of the crew and first responders prevented any property damage to anything except the plants directly under the burning helicopter.
This success by the crew and emergency workers had positive consequences beyond protecting the life and health of the passengers and local population. American military aviation in the area is extremely controversial, and nearly all incidents on the island trigger local protests and condemnation from politicians. Limiting the property damage and protecting all human life reduces the amount of backlash.
Capt. Ryan J. Boyer, Capt. Molly A. O’Malley, and Sgt. Garrett D. Mills pose with their air medals and a CH-53 Super Stallion after their award ceremony.
(U.S. Marine Corps Sgt. Dominic Romero)
The Marine Corps’ fleet of CH-53E Super Stallions are quickly becoming obsolete as their heavy rate of use in ongoing conflicts across the world — as well as normal operations and training — take a toll. The average CH-53E is 15 years old.
The aircraft is being replaced by the CH-53K, a very similar version of the helicopter but with a significantly more capability.
See more photos from the award ceremony below:
A U.S. Marine receives the Air Medal from Maj. Gen. Kevin M. IIams during a July 24 ceremony honoring three Marines’ quick actions during an Oct. 11, 2017 in-flight fire.
(U.S. Marine Corps Sgt. Dominic Romero)
Capt. Ryan J. Boyer, Capt. Molly A. O’Malley, and Sgt. Garrett D. Mills stand during an award ceremony as Maj. Gen. Kevin M. IIams gives his remarks.
(U.S. Marine Corps Sgt. Dominic Romero)
Capt. Ryan J. Boyer, Capt. Molly A. O’Malley, and Sgt. Garrett D. Mills stand in front of Maj. Gen. Kevin M. IIams during a July 24 award ceremony honoring their actions during an Oct. 11, 2017 fire in their CH-53E Super Stallion.
Moments after Rep. Steve Scalise (R-La.), the U.S. House Majority Whip, was shot in the hip during an attack on a practice for the upcoming Congressional baseball game, an Iraq War vet was treating his wound.
“You never expect a baseball field in America to feel like being back in a combat zone in Iraq, but this morning it did,” Rep. Brad Wenstrup tweeted. The Ohio Republican congressman later told an aide the only difference between the Alexandria shooting and Iraq was being “without his weapon.”
According to a report by WLWT.com, Wenstrup began to treat his wounded colleague after Scalise dragged himself off the field. Wenstrup had seen wounds like that before he had ever entered politics.
According to the official biography on his web site, that is because Rep. Wentrup is also Col. Wenstrup in the U.S. Army Reserve – and he’s has served in the Army Reserve since 1998, after his sister had a battle with leukemia. During a tour in Iraq with the 344th Combat Support Hospital, Wenstrup was a combat surgeon, which he described as “the worst thing that ever happened to me, and the best thing I ever got to do.”
“I remember one Marine we lost on the table, and the anesthesiologist saying, ‘I had breakfast with him this morning.’ Or having to tell a group of Marines their buddy didn’t make it. Those were the tough days,” he told the college’s magazine.
He had good days, too, including helping to treat a four-month old girl who had pneumonia. Eventually, the doctors figured out the girl also needed gluten-free formula, and raised over $400 to help make arrangements for a U.S. company to send the girl’s father the right baby food.
It took sixty five years for one member of the 101st Airborne Division Screaming Eagles to learn that his actions during the Battle of Bastogne were legendary, but not for heroism or bravery. It all started with a simple request for a beer – and the greatest beer run the world will ever see.
Vincent Speranza, Vince to all that know him, had joined the Army right after graduating high school in 1943 and was assigned to Company H, 501st Parachute Infantry Regiment, 101st Airborne as a replacement soldier while the unit recovered from Operation Market-Garden.
Shortly after training, Vince found himself in a foxhole in the middle of Bastogne, Belgium – cold, short on supplies, food, and ammunition. And surrounded by German troops.
“The first eight days we got pounded” by German artillery, he recalled. “But this was the 101st. They could not get past (us). They never set one foot in Bastogne.”
On the second day, his friend Joe Willis took shrapnel to both legs and was pulled back to a makeshift combat hospital inside a mostly destroyed church. Vince tracked him down and asked if there was anything he could do for his friend.
Vince told him it was impossible. The 101st was surrounded by Germans with no supplies coming in, they were taking artillery fire every day, and the town had been bombarded. But Joe wanted a beer.
Moving through the town, Vince, from blown-out tavern to blown-out tavern, went searching until serendipity hit. At the third tavern he hit, Vince pulled on a tap and beer came flowing out. He filled his helmet – the same one used as a makeshift shovel and Porta Potty in the foxhole – with all the beer he could handle and returned to the hospital.
Mission accomplished. Vince poured beer for Joe and some of those around him. When the beer ran out, they asked him to go for more.
As he returned to the hospital, Vince was confronted by a Major who demanded to know what he was doing.
“Giving aid and comfort to the wounded,” was the paratrooper’s simple answer.
An ass-chewing about the dangers of giving beer to men with gut and chest wounds lead to Vince putting his helmet back on his head, beer pouring down his uniform, and heading out.
While that could have been the end of it, the story continues 65 years later, when Vince returned to Bastogne for an anniversary celebration and learned that his epic beer run had been turned into Airborne beer, typically drunk out of a ceramic mug in the shape of a helmet.
With Russia’s announcement of a new permanent naval base in Tartus, Syria – long a port used by Russian (and prior to 1991, Soviet) forces, Moscow’s expansion into that war torn country continues even as the Assad regime is wracked by civil war.
But Russia has had a long history in the Med.
Tartus Naval Base has been used by the Russians since 1971. In those 45 years, it served as a forward operating location for the Fifth Eskadra (5th Operational Squadron). This unit was intended to counter the presence of the U.S. Sixth Fleet in the Med. The base had not been able to permanently support major vessels like the Kuznetov-class carrier; the Kirov-class battlecruisers; the Slava-class cruisers; or even modern destroyers and frigates in Russian service. The new construction at the base is intended to make it a permanent base for carriers and larger vessels as opposed to just a place to park.
The Fifth Eskadra was formed in 1967 after the Egypt-Israel Six Day War. The Soviets had been unable to find a way to inflict damage on the Sixth Fleet in the event of a war with the United States. This was not a solid strategic position from its perspective, and Russian naval legend Sergei Gorshkov pestered his superiors until the unit was formed.
The unit usually consisted of as many as 80 vessels, including two guided-missile cruisers and a number of smaller escorts like the Mod Kashin-class destroyer or Krivak-class frigate, ten diesel-electric submarines, and a host of auxiliary vessels. The Sixth Fleet usually had half that total, but much of its strength would be concentrated in a carrier battle group which could make life exciting (not to mention short) for the Soviet vessels.
After the collapse of the Soviet Union, the Russians disbanded the Fifth Eskadra at the end of 1992 — a little over 25 years after the squadron was formed. Two decades later, in 2013, the Russians re-formed the squadron as the Syrian civil war heated up.
Now with about 10 vessels, it is a shadow of the force that faced off with the Sixth Fleet. Still, it is a sign that Russia is reasserting itself in the region.
“It would be illogical to continue to concentrate our forces on a few large ships. The adversary will quickly recognize that striking while concentrated (aboard ship) is the preferred option. We need to change this calculus with a new fleet design of smaller, more lethal, and more risk-worthy platforms.”
Basically, the old ways of landing Marines are really old and need to be updated – because even the most poorly armed insurgents can take down one of those old amphibs.
Gen. Berger sees
Marine Corps Commandant Gen. David H. Berger’s first big move in his new post is to offer a stinging critique of the way Marines operate in amphibious landings. He issued a 26-page document to his lower commanders that calls the current method of moving Marines to shore aboard slow-moving amphibious vehicles and helicopters “impractical and unreasonable” and “not organized, trained, or equipped to support the naval force” in combat.
The Navy’s requirement for Marines to make their way to the shore uses 38 lumbering amphibious ships that are waiting offshore once the fighting begins. The new Commandant thinks that modern defenses such as China’s anti-air and anti-ship net in the South China Sea make this strategy impractical and risky.
“We must divest of legacy capabilities that do not meet our future requirements, regardless of their past operational efficacy,” Berger wrote.
Gen. Robert Neller passes the Marine Corps flag to the 38th Commandant of the Marine Corps, Gen. David H. Berger
General Berger earlier called for Marines to have long-range fires that can operate from a ship or shore-based batteries that can fight other sea or shore-based batteries while giving amphibious ships time and room to maneuver. The Commandant is concerned that the way the Corps operates now will be detected and contested by any potential enemy waiting to kill a few thousand Marines before they can land on its beaches.
The entire ethos is outlined in the 38th Commandant’s Planning Guidance (CPG) document and focuses on his five priority areas: force design, warfighting, education and training, core values, and command and leadership. In the CPG, Gen. Berger sums up his vision in bold letters:
“The Marine Corps will be trained and equipped as a naval expeditionary force-in-readiness and prepared to operate inside actively contested maritime spaces in support of fleet operations.”
On his fantastic new album A Sailor’s Guide to Earth, Sturgill Simpson uses life at sea to inspire songs about separation from family and a longing for home. Simpson himself grew up in Kentucky and claims he joined the Navy on a whim when driving past a recruiting station.
After three years which included service in Japan and Southeast Asia, he left the service. “I wasn’t very good at taking orders,” he told Garden and Gun in 2014.
After he came home and started a music career, it turned out he wasn’t very good at taking orders from Nashville, either. Simpson wasn’t cut out for the kind of trucks-and-beer pop country that’s dominated the charts over the last decade and made his name on independently-released albums. He had a breakthrough with 2014’s Metamodern Sounds in Country Music, produced by Dave Cobb (who’s made a name for himself producing fellow Nashville rebels Chris Stapleton and Jason Isbell).
Atlantic Records signed Simpson and gave him total freedom to make Sailor’s Guide, which he produced himself. What he made is a compact album (39 minutes, just like the old days!) that combines ’70s Waylon Jennings and Willie Nelson with Stax Records-style horns, Al Green keyboard grooves and a Elvis in Memphis vibe.
On the track “Sea Stories,” he talks about joining the Navy:
Basically it’s just like papaw says:
“Keep your mouth shut and you’ll be fine”
Just another enlisted egg
In the bowl for Uncle Sam’s beater
When you get to Dam Neck
Hear a voice in your head
Saying, “my life’s no longer mine”
He also includes a cover of Nirvana’s “In Bloom,” where he adds a new lyric. After the line “You don’t know what it means” (where there’s a howling guitar squall on the original version), Simpson sings “to love someone,” a line he says he imagined was there for years after he first heard the Nirvana version. Fans of the BeeGees (and the innumerable soul covers of the song) will appreciate the “To Love Someone” reference.
There’s zero Autotune on the vocals, so this kind of gritty, soulful music may sound a bit weird to fans of Little Big Town or Florida-Georgia Line. None of the songs sound like truck commercials, so you’re probably not going to hear this music on commercial country radio. If Chris Stapleton got your attention last year, though, Simpson’s album is a logical next step into the world of traditional country.
The album’s for sale in all the digital music stores, CDs are really cheap at Amazon and you can stream it on Spotify or Apple Music before you buy. Check out the first two videos from the album below.
Sturgill’s daring cover of Nirvana’s “In Bloom”The album’s first single is “Brace for Impact (Live a Little)”
In early July, the Michael E. DeBakey VA Medical Center became the first VA facility to participate in an international clinical trial evaluating the therapeutic benefit of an immunomodulator drug, Tocilizumab (TCZ), as a treatment for Veterans with COVID-19 severe pneumonia.
“COVID-19 is known to cause extensive damage in the lungs,” said Dr. Lavannya Pandit, a Houston VA pulmonologist and critical care physician who is a co-investigator in the study. “This often leads to difficulty breathing and, eventually, pneumonia. Pneumonia triggers a hyperimmune response that we are seeing can be more detrimental to some patients than the original infection.”
Medical personnel have used TCZ successfully to treat hyperimmune responses in cancer patients. The trial results will help determine if TCZ has a similar effect in patients who are diagnosed with severe COVID-19 pneumonia.
The clinical trial is a randomized, placebo-controlled study. Both the investigator and participant are blinded to who is receiving the TCZ treatment. Eligible participants are patients who are in the hospital and who chest imaging has confirmed has severe COVID-19 pneumonia.
Veterans at Houston VA very willing to step up
Medical personnel will monitor Veterans in a clinical environment for their responses to the treatment. Responses may include disease progression, the duration of hospitalization and the need for critical care and other supportive treatments.
“VA offers cutting-edge treatments and top quality care for Veterans with COVID-19,” said Dr. Barbara Trautner. Trautner is a faculty member at the Behavioral Health Program, Center for Innovations in Quality, Effectiveness and Safety at the Michael E. DeBakey VA Medical Center.
“Participating in this clinical trial allows our Veterans the opportunity to contribute to scientific progress,” she said. “So far, Veterans at the Houston VA have been very willing to step up and volunteer. We enrolled eight Veterans in the first three days of the study.”
Trial taking place in more than 50 locations
“The treatments we offer for COVID-19 three months from now will be very different than what we offer today because of scientific trials like this,” said Trautner.
In addition to Houston VA, the trial is taking place in more than 50 locations across the United States, Europe and Canada, including at the Baylor College of Medicine.
“I always find it an honor and privilege to care for our Veterans who have served our country,” Trautner said. “The Veterans we are enrolling in this study are eager to join the fight against COVID-19, and we are happy to provide them this opportunity and do our part.”
Learning to live everywhere is a unique skill military families possess, yet when it comes to determining the infamous final move, infinite possibilities make going home quite complicated. Complicated just got a lot easier thanks to Navy Federal’s 2020 “Best Cities After Service” list.
Determining America’s top choices for veterans took into consideration feedback from over 1,000 military and civilians analyzing metrics such as crime, VA options, recreation, cost of living and job opportunities specific to veteran employment trends.
Clay Stackhouse, Regional Outreach Manager for Navy Federal explained, “The list was created after considering COVID’s impact on the job market and daily life. With remote work possibilities on the rise, the need to live in big cities simply for work is not there.” Great news for often-tight, post-service budgets.
Compared to the 2018 best cities list, which had a large heartland concentration, the biggest switch has been giving more weight to the location itself. It seems like as the globe slowed to a screeching halt this year, the world and military community alike took inventory of what makes life actually meaningful. So, move over economics, it’s time to take a hike—literally.
While work-life balance may have gone to the wayside when the mission came first, civilian life holds endless possibilities to truly dig into a place, experiencing and enjoying everything it has to offer.
Several southern coastal cities made the cut, offering charm at a much more affordable price point compared to San Diego, which came in at number six. If four seasons are more your style, consider living in Duluth, the “craft beer capital of Minnesota” or surrounding yourself with rivers and seafood staples in Norwich.
Small town America is making a comeback, evident in many of the top choices. Also on the rise are mid-sized cities like Fort Worth, bringing big city perks and strong business networking opportunities to the table without having to squeeze your family into a 5th-floor walk-up.
Stackhouse explains that no matter where you live, it is the Veteran community that makes a place truly great, not the other way around. All of the cities on this year’s list have strong Veteran communities ready to support incoming service members and their families. Ready to help them navigate this transition successfully.
“You never do anything in the military alone, no matter how small your unit is,” says Stackhouse. Choosing any one of the cities on this list is stepping forward into a community vetted by the best of your own.
Researchers have identified a compound that blocks the spread of pancreatic and other cancers in various animal models. When cancer spreads from one part of the body to another in a process called metastasis, it can eventually grow beyond the reach of effective therapies. Now, there is a new plan of attack against this deadly process, thanks to scientists at the National Institutes of Health, Northwestern University and their collaborative research partners.
The team collaborated to identify a compound, which they named metarrestin, that stopped tumor metastasis in multiple animal models. Mice treated with metarrestin also had fewer tumors and lived longer than mice that did not receive treatment. These results were published May 16, 2018, in Science Translational Medicine.
In patients, metarrestin potentially could be effective as a therapy after cancer surgery. Because advanced cancers are difficult to completely remove with surgery, doctors typically give chemotherapy to try to kill undetected cancer cells left behind and prevent the cancer from coming back. Metarrestin could be added to such standard drug therapy.
Metarrestin breaks down an incompletely understood component of cancer cells called the perinucleolar compartment (PNC). PNCs are found only in cancer cells, and in a higher number of cells in advanced cancer, when it has spread to other sites in the body.
Co-author Sui Huang, M.D., Ph.D., and her colleagues at Northwestern University Feinberg School of Medicine, Chicago, showed early on that the more cancer cells with PNCs in a tumor, the more likely it would spread. Her findings suggested that reducing PNCs might translate to less cancer progression and possibly better outcomes in patients.
To test these ideas, Huang approached Marugan to tap into NCATS’ expertise in screening, chemistry, compound development and testing to evaluate more than 140,000 compounds for their potential effectiveness in eliminating PNCs in cells in advanced cancer.
While nearly 100 compounds initially showed some activity, the investigators identified one compound that could effectively break down PNCs in advanced prostate cancer cells. With the help of researchers at the University of Kansas, Lawrence, they modified the compound to make it work better as a potential drug and evaluated the effects of the molecule in different assays, or tests, in the laboratory. They found that metarrestin could block the way prostate and pancreatic cancer cells spread.
In collaboration with co-author Udo Rudloff, M.D., Ph.D., from NIH’s National Cancer Institute’s (NCI) Center for Cancer Research, the group evaluated the effects — including toxicity — of metarrestin in pancreatic cancer mouse models. The investigators found that it prevented the further spread of pancreatic cancer by disrupting the protein-making machinery of cancer cells, and mice treated with metarrestin lived longer than mice without treatment.
“Cancer cells are rapidly dividing and need to make more proteins than healthy cells to help carry out various activities, including the ability to spread,” Rudloff said. “Interfering with the system stalls cancer cell metastasis.”
Rudloff and his NCI group currently are working with scientists at the NCATS-led Bridging Interventional Development Gaps program to collect the pre-clinical data on metarrestin needed to further its development as a candidate drug. The scientists plan to file an Investigational New Drug (IND) application in the fall with the U.S. Food and Drug Administration (FDA). FDA IND approval is necessary before a candidate drug can be tested in patients.
The research was funded by NCATS and NCI through their intramural programs, and in addition, the National Human Genome Research Institute grant U54HG005031, the National Institute of General Medical Sciences grants R01GM078555 and R01GM115710, NCI grant 2 P30 CA060553-19, the V Foundation, a donation from the Baskes family to the Robert H. Lurie Comprehensive Cancer Center, donations from ‘Running for Rachel’ and the Pomerenk family via the Rachel Guss and Bob Pomerenk Pancreas Cancer Research Fellowship to NCI, the Robert H. Lurie Comprehensive Cancer Center – Translational Bridge Program Fellowship in Lymphoma Research and the Molecular Libraries Initiative funding to the University of Kansas Specialized Chemistry Center.
About the National Center for Advancing Translational Sciences (NCATS): NCATS conducts and supports research on the science and operation of translation — the process by which interventions to improve health are developed and implemented — to allow more treatments to get to more patients more quickly. For more information about how NCATS is improving health through smarter science, visit https://ncats.nih.gov.
About the National Institutes of Health (NIH): NIH, the nation’s medical research agency, includes 27 Institutes and Centers and is a component of the U.S. Department of Health and Human Services. NIH is the primary federal agency conducting and supporting basic, clinical, and translational medical research, and is investigating the causes, treatments, and cures for both common and rare diseases. For more information about NIH and its programs, visit www.nih.gov.
After months of delay, the Trump administration is finalizing plans to revamp the nation’s military command for defensive and offensive cyber operations in hopes of intensifying America’s ability to wage cyber war against the Islamic State group and other foes, according to US officials.
Under the plans, US Cyber Command would eventually be split off from the intelligence-focused National Security Agency.
Details are still being worked out, but officials say they expect a decision and announcement in the coming weeks. The officials weren’t authorized to speak publicly on the matter so requested anonymity.
The goal, they said, is to give US Cyber Command more autonomy, freeing it from any constraints that stem from working alongside the NSA, which is responsible for monitoring and collecting telephone, internet, and other intelligence data from around the world — a responsibility that can sometimes clash with military operations against enemy forces.
Making cyber an independent military command will put the fight in digital space on the same footing as more traditional realms of battle on land, in the air, at sea, and in space.
The move reflects the escalating threat of cyberattacks and intrusions from other nation states, terrorist groups, and hackers, and comes as the US faces ever-widening fears about Russian hacking following Moscow’s efforts to meddle in the 2016 American election.
Experts said the command will need time to find its footing.
“Right now I think it’s inevitable, but it’s on a very slow glide path,” said Jim Lewis, a cybersecurity expert with the Center for Strategic and International Studies. But, he added, “A new entity is not going to be able to duplicate NSA’s capabilities.”
The NSA, for example, has 300 of the country’s leading mathematicians “and a gigantic super computer,” Lewis said. “Things like this are hard to duplicate.”
He added, however, that over time, the US has increasingly used cyber as a tactical weapon, bolstering the argument for separating it from the NSA.
The two highly secretive organizations, based at Fort Meade, Maryland, have been under the same four-star commander since Cyber Command’s creation in 2009.
But the Defense Department has been agitating for a separation, perceiving the NSA and intelligence community as resistant to more aggressive cyber warfare, particularly after the Islamic State’s transformation in recent years from an obscure insurgent force into an organization holding significant territory across Iraq and Syria and with a worldwide recruiting network.
While the military wanted to attack IS networks, intelligence objectives prioritized gathering information from them, according to US officials familiar with the debate. They weren’t authorized to discuss internal deliberations publicly and requested anonymity.
Then-Defense Secretary Ash Carter sent a plan to President Barack Obama last year to make Cyber Command an independent military headquarters and break it away from the NSA, believing that the agency’s desire to collect intelligence was at times preventing the military from eliminating IS’ ability to raise money, inspire attacks, and command its widely dispersed network of fighters.
Carter, at the time, also pushed for the ouster of Adm. Mike Rogers, who still heads both bodies. The Pentagon, he warned, was losing the war in the cyber domain, focusing on cyberthreats from nations such as Iran, Russia, and China, rather than on countering the communications and propaganda campaigns of internet-savvy insurgents.
Officials also grew alarmed by the growing number of cyberattacks against the US government, including several serious, high-level Defense Department breaches that occurred under Rogers’ watch.
“NSA is truly an intelligence-collection organization,” said Lauren Fish, a research associate with the Center for a New American Security. “It should be collecting information, writing reports on it. Cyber Command is meant to be an organization that uses tools to have military operational effect.”
After President Donald Trump’s inauguration, officials said Defense Secretary Jim Mattis endorsed much of the plan. But debate over details has dragged on for months.
It’s unclear how fast the Cyber Command will break off on its own. Some officials believe the new command isn’t battle-ready, given its current reliance on the NSA’s expertise, staff, and equipment. That effort will require the department to continue to attract and retain cyber experts.
Cyber Command was created in 2009 by the Obama administration to address threats of cyber espionage and other attacks. It was set up as a sub-unit under US Strategic Command to coordinate the Pentagon’s ability to conduct cyber warfare and to defend its own networks, including those that are used by combat forces in battle.
Officials originally said the new cyber effort would likely involve hundreds, rather than thousands, of new employees.
Since then, the command has grown to more than 700 military and civilian employees. The military services also have their own cyber units, with a goal of having 133 fully operational teams with as many as 6,200 personnel.
Its proposed budget for next year is $647 million. Rogers told Congress in May that represents a 16 percent increase over this year’s budget to cover costs associated with building the cyber force, fighting IS, and becoming an independent command.
Under the new plan being forwarded by the Pentagon to the White House, officials said Army Lt. Gen. William Mayville would be nominated to lead Cyber Command. Leadership of the NSA could be turned over to a civilian.
Mayville is currently the director of the military’s joint staff and has extensive experience as a combat-hardened commander. He deployed to both Iraq and Afghanistan, leading the 173rd Airborne Brigade when it made its assault into Iraq in March 2003 and later heading coalition operations in eastern Afghanistan.