It's well known that cats will always land on their feet when dropped. According to this clip, those cat-like reflexes are completely lost in a weightless environment.
Along with cats the Airmen also fly pigeons in a weightless state, and some of them wound up flying upside down.
The 1947 video was part of the U.S. Air Force's aerospace medical research lab's bioastronautics research in Dayton, Ohio.
Watch the full 13-minute video here, which includes pretty nifty slow-motion ejection seat footage (not using cats).